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Urgent! Principal UI Engineer Job at OpenEye Scientific in Boston Job Opening In Boston – Now Hiring OpenEye Scientific

Principal UI Engineer Job at OpenEye Scientific in Boston



Job description

Over the last eight years, OpenEye Scientific has developed the field's most advanced large-scale compute platform, Orion, built on Amazon Web Services.

In this position, you will be working at the cutting edge of cloud computing, C++/Python development, and advanced MD simulation techniques.

Your work will have the potential to make a major impact in drug discovery, and will be available to many pharmaceutical and biotech companies.



Scientists around the world use Orion for early-stage drug discovery and design in the pursuit of improving human health.

Orion combines the power of advanced HPC, computational methods, and in-browser 3D visualization & modeling to solve problems in drug discovery & design.

Our innovative solutions enable customers to routinely model billions of compounds in-silico.

Orion enables our customers to interactively explore chemical space, evaluate designs and gain scientific understanding.



As a Principal UI Engineer, you will work with designers, scientists, and software engineers to enhance & extend Orion's UI capabilities.

You'll have the chance to work on a multitude of interesting challenges across scientific visualization, collaboration, data management, as well as new product & feature development.

You'll be part of a team building cutting edge features, as well as helping to modernize existing software.



Minimum Qualifications:

  • BS in computer science/engineering, biology/chemistry or similar with a minimum of 7 years of experience OR MS with a minimum of 5 years of experience OR PhD with a minimum of 1 year of experience
  • Experience designing, developing, troubleshooting and debugging complex user interfaces and software systems as part of a team
  • Expert in JavaScript/Typescript/CSS/HTML
  • Experience with Vue, Pinia/VueX and application frameworks such as Nuxt.js / Next.js.

  • Experience in Life Sciences, HPC, Python, AWS, Web Workers, WebAssembly, and WebGL are a plus
  • Experience with unit & end-to-end testing, CI/CD, source control, code review, comfortable using command line interfaces
  • Strong background of computer science fundamentals (data structures, algorithms)
  • Passionate to learn and explore new technologies and demonstrates good analysis and problem-solving skills
Interpersonal skills required:
  • Ability to establish a close working relationship with peers in development, science, design and customer success, often across time zones
  • Take initiative to solve unexpected challenges during development
  • Willing to expand their knowledge and skills in both technical and scientific areas
  • Push to raise the bar while always operating with integrity


OpenEye, Cadence Molecular Sciences, an industry leader in computational molecular design, uses a scientific approach to deliver rapid, robust, and scalable software, toolkits, and technology & design services for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors

The annual salary range for Massachusetts is $117,600 to $218,400.

You may also be eligible to receive incentive compensation: bonus, equity, and benefits.

Sales positions generally offer a competitive On Target Earnings (OTE) incentive compensation structure.

Please note that the salary range is a guideline and compensation may vary based on factors such as qualifications, skill level, competencies and work location.

Our benefits programs include: paid vacation and paid holidays, 401(k) plan with employer match, employee stock purchase plan, a variety of medical, dental and vision plan options, and more.



We're doing work that matters.

Help us solve what others can't.


Required Skill Profession

Computer Occupations



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