Job Summary
The Department of Chemistry and Biochemistry seeks to hire a Post-Doctoral Fellow to develop microbial heterologous expression systems via synthetic biology technologies, aiming to utilize the vast genetic potentials of the biosynthetic gene clusters from cultivatable microbes for production of bioactive natural products, such as antibiotics and anticancer agents.
Following the establishment of a high efficiency heterologous expression system, the selected promising biosynthetic gene clusters will be cloned/synthesized and expressed in this heterologous expression system for production of the corresponding compounds.
The production level and chemical diversity will be further tuned by genetic manipulation.
In addition, the biological and/or physiological activities of the compounds discovered will be studied.
Additional job responsibilities include contributing to writing manuscripts and reports on funded projects and assisting in training graduate and undergraduate students in their research.
Job Related Minimum Required Education and ExperiencePhD in Chemistry, Biochemistry, Biology or a closely related science with experience in microbial genetics, gene editing, and synthetic biology.
Required Certification, Licensure/Other Credentials Preferred Qualifications Knowledge/Skills/AbilitiesKnowledge of microbial genetics and synthetic biology are required; Enzymology, natural products chemistry, and biological evaluation would be a plus.
Strong communication and writing abilities are also required.
Develop microbial heterologous expression systems via synthetic biology technologies, aiming to utilize the vast genetic potentials of the biosynthetic gene clusters from cultivatable microbes for production of bioactive natural products.
Essential Function Yes Percentage of Time 40 Job DutyAssists in supervising and training graduate and undergraduate students in their research projects.
Essential Function Yes Percentage of Time 20 Job DutyContribute to writing manuscripts and reports on funded projects.
Essential Function Yes Percentage of Time 20 Job DutyBiological and/or physiological activities of the compounds discovered will be studied.
Essential Function Yes Percentage of Time 20 Position Attributes Hazardous weather category Non-Essential Employees in Safety-Sensitive or Security-Sensitive positions will be subject to pre-employment and post-employment drug testing in accordance with University policy HR Drug and Alcohol Testing.Required fields are indicated with an asterisk (*).