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Scientist 2 - Research and Development Job Opening In San Diego – Now Hiring Net2Source


Job description


Join a Global Leader in Workforce Solutions – NetSource Inc.


Who We Are

NetSource Inc.

isn't just another staffing company, we're a powerhouse of innovation, connecting top talent with the right opportunities.

Recognized for % growth in the past three years, we operate in countries with a global team of ,+.

Our mission?

To bridge the talent gap with precision—Right Talent.

Right Time.

Right Place.

Right Price.

Job Title: Scientist I, Oligonucleotide Analytics

Location: La Jolla, CA

% Onsite

Duration: months contract

Notes from HM:

- PhD is required

- Must have experience with Analytical Chemistry

- Must have experience with Oligonucleotides

- Must have siRNA experience

- Previous gene therapy experience

- Must have - years of experience

- Experience with Chromatography (LC-MS)

- Experience with these instruments: Thermo LTQ, LC/MS or Thermo Orbitrap LC/MS



Key Responsibilities:

% • Operating LC-MS systems to perform in-process and final QC of various scales of highly modified oligonucleotides, including siRNA and ASO, to support both discovery portfolio and pre-portfolio projects

% • Optimize methods and improve analytical capabilities for Client Oligonucleotide synthesis

% • Analyze and optimize methods in a project-specific way ( GalNAc vs Cholesterol vs C) by denaturing and non-denaturing HPLC methods.

In addition, phosphoramidites or lipids by HPLC and LCMS.

% • Establish and automate high throughput analytical capabilities and coordinate those efforts with higher synthesis throughput.

% • Analyze oligonucleotides by HPLC-SEC, RP-IP and Ion-Exchange Chromatography.

• Continue optimizing siRNAs using best-in class analytical chemistry methodologies such as different column matrixes for optimal siRNA characterization

• Support integrity confirmation requests (such as concentration) by assay development and biology teams

% • Conduct QC for lipid nanoparticle (LNP) formulations of mRNA

% • Ensure the supply of laboratory consumables and reagents are in stock as needed

• Maintain a high level of productivity in the laboratory setting.

% • Present data and reports on project status at individual, group, and departmental meetings.



Qualifications

• with - years of experience, performing progressively advanced duties at the Scientist level, or the equivalent training/experience is required.

• Prior experience in the characterization of oligonucleotides and/or nucleoside/nucleotide analytes is required.



Top Three Skills: Operate LC-MS systems - Analyze and optimize methods - establish and automate high throughout analytical capabilities



Why Work With Us?

We believe in more than just jobs—we build careers.

At NetSource, we champion leadership at all levels, celebrate diverse perspectives, and empower you to make an impact.

Think work-life balance, professional growth, and a collaborative culture where your ideas matter.



Our Commitment to Inclusion & Equity

NetSource is an equal opportunity employer, dedicated to fostering a workplace where diverse talents and perspectives are valued.

We make all employment decisions based on merit, ensuring a culture of respect, fairness, and opportunity for all, regardless of age, gender, ethnicity, disability, or other protected characteristics.



Awards & Recognition

• America's Most Honored Businesses (Top %)

• Fastest-Growing Staffing Firm by Staffing Industry Analysts

• INC List for Eight Consecutive Years

• Top by Dallas Business Journal

• Spirit of Alliance Award by Agile



Ready to Level Up Your Career?

Click Apply Now and let's make it happen.

Required Skill Profession

Life Scientists


  • Job Details

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Unlock Your Scientist 2 Potential: Insight & Career Growth Guide


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Are You Looking for Scientist 2 Research and Development Job?

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