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Urgent! Scientist, Clinical Biomarker Laboratory, Flow Cytometry Job Opening In Norwood – Now Hiring Moderna

Scientist, Clinical Biomarker Laboratory, Flow Cytometry



Job description

The Role:

Moderna is seeking a motivated and skilled Scientist to join the Clinical Flow Cytometry group.

This individual will serve as the Cytometer Instrument Lead while also executing clinical testing, assay/panel development, and validation activities under GCLP guidelines.

The Scientist will work with a team of scientists to deliver high-quality biomarker data to support clinical programs across multiple therapeutic areas.

The successful candidate will have strong technical expertise in spectral flow cytometry instrumentation (Cytek Aurora), along with experience in developing, validating, and executing flow cytometry–based assays.

This role requires deep understanding of immunology, experience in clinical laboratory environments, and the ability to apply best practices in translational and clinical sample testing.

You will be an integral part in applying high parameter flow and complex assays to generate key clinical data to drive clinical trial decisions.

Here's What You’ll Do: 

  • Serve as an internal technical expert (Instrument Lead) for flow cytometry instrumentation, operation, and maintenance.

  • Ensure all cytometers are harmonized to generate equivalent data, remain ready for clinical acquisition, adhere to stringent QC program and that all documentation meets GCLP Compliance needs and is available in the event of internal or external audit.

  • Identify and troubleshoot instrumentation, assay, or workflow issues; implement mitigation strategies to avoid downtime or data loss.

  • Responsible for Data Management and database backups adhering to GCLP Compliance and Regulatory needs

  • Work with and guide Global Instrument Leads on maintenance, harmonization, and documentation practices.

  • Train and mentor junior staff in flow cytometry methods, instrumentation, and assay execution.

  • Execute clinical sample testing under GCLP guidelines, including PBMC and whole blood processing, staining, and high-parameter immunophenotyping.

  • Adhere to established experimental workflows and documentation procedures while working to improve processes and documents for accuracy and efficiency.

  • Design, develop, and optimize multiparameter flow cytometry panels and assays, including ex vivo functional profiling (e.g., intracellular cytokine staining, proliferation, cell activation).

  • Lead or support assay fit-for-purpose qualification and validation to ensure compliance with clinical standards.

  • Perform data acquisition, gating analysis (FCS Express), interpretation, and reporting of study data.

  • Contribute to analytical study documentation including SOPs, study plans, and study reports as needed.

  • Stay current with emerging technologies, reagents, and industry best practices in clinical cytometry.

  • Occasionally the job may require overtime work or weekend shift as needed

Here’s What You’ll Bring to the Table:

  • Ph.D., MS or BS in Immunology, Life Sciences, Biology, or related field; 5yr+ experience in translational/clinical biomarker flow cytometry

  • Strong expertise with flow cytometry instrumentation (Cytek Aurora, BD Symphony/Fortessa, or equivalent) including set-up, troubleshooting, and routine maintenance.

  • Proven experience in clinical laboratory environments with adherence to GCLP or other regulated standards.

  • Demonstrated success in designing, developing, and validating multiparameter flow cytometry assays for clinical applications.

  • Hands-on experience in immunology-based functional assays (intracellular cytokine staining, T cell immunophenotyping, receptor occupancy assays).

  • High proficiency with flow cytometry analysis software (FCS Express, FlowJo, OMIQ) and data interpretation.

  • Strong organizational, computational, and documentation skills (Excel, GraphPad Prism, PowerPoint, Word).

  • Excellent written, presentation, and interpersonal communication skills; ability to collaborate effectively across teams and with external partners.

  • Track record of flexibility, problem-solving, and adaptability to shifting priorities in a fast-paced environment.

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Lifestyle Spending Accounts to personalize your well-being journey
  • Family planning and adoption benefits
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities
  • Location-specific perks and extras


Required Skill Profession

Life Scientists



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