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Title: Scientist/Engineer II – Vaccine Drug Product Development
Duration: months contract
Location: West Point, PA (% Onsite)
Position Summary
Vaccine Drug Product Development, a part of client's Research Laboratories in West Point, PA, is seeking a Contract Scientist or Engineer to join the team.
The selected candidate will work on the design and development of vaccine drug products from preclinical through Phase III, with a focus on commercialization readiness.
This is a hands-on laboratory position requiring collaboration with cross-functional teams to develop the next generation of vaccine formulations and delivery systems.
Responsibilities
• Design and perform hypothesis-driven formulation and process development experiments for sterile vaccine drug products (buffers, stabilizers, antigen/adjuvant, vials, syringes) across multiple modalities (subunit, conjugate, live-attenuated, etc.)
• Prepare formulations and fill vials/syringes for characterization and animal studies using aseptic technique and Good Laboratory Practices (GLP); support technology transfer to GMP manufacturing
• Conduct stability and forced-degradation studies; analyze data, summarize findings, and author technical reports and electronic notebook entries
• Operate and troubleshoot benchtop unit operations (mixing, filtration, pumping, lyophilization), common lab instruments (pH meters, balances, pipettes), and analytical tools (DLS, SLS, KF, DSC, DSF)
• Collaborate with discovery, analytical, manufacturing, and regulatory teams to achieve project deliverables and timelines
• Stay current with scientific literature and emerging technologies to enhance formulations and processes
• Support analytical characterization of formulated products such as osmolality, viscosity, pH, and dynamic light scattering
• Maintain laboratory compliance, cleanliness, and safety standards
• Draft, review, and execute protocols for batch manufacturing
Qualifications
Minimum Education Requirement:
• in Chemistry, Biology, Biochemistry, Biophysics, Chemical/Biochemical Engineering, Virology, or related discipline with – years of relevant experience
OR
• in Chemistry, Biology, Biochemistry, Biophysics, Chemical/Biochemical Engineering, Virology, or related discipline with – years of relevant experience
Required Skills and Experience:
• Hands-on laboratory experience (academic or industry) in designing, executing, and interpreting experiments
• Excellent communication, writing, and collaboration skills
• Strong organizational and problem-solving abilities
• Comfortable working in a fast-paced environment and adapting to change
• Ability to provide critical input into experimental design and analysis
• Team-oriented, motivated to learn, and able to manage multiple priorities under technical supervision
Desired Skills and Experience:
• Analytical characterization experience with biotherapeutics (, particle size analysis, biophysical techniques)
• Formulation development experience with RNA, carbohydrate, protein, or live viral vaccines, and adjuvants
• Demonstrated proficiency in aseptic technique
• Understanding of drug product manufacturing processes and scale-up
• Experience in preparation or manufacturing of safety assessment or clinical supplies
• Experience authoring source documents for regulatory submissions
• Familiarity with lyophilization and methods to assess residual moisture and physical properties of lyophilized formulations
Preferred Candidates
Candidates with hands-on experience in formulation, filtration, analytical/biochemical/biophysical characterization, and process development will be highly preferred.
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