Technical Project Manager

Job description

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Summary

RayzeBio is seeking a dynamic and experienced Technical Project Manager with a strong engineering background and substantial capital project management expertise to lead the construction and operational ramp-up of a new radiopharmaceutical manufacturing facility in Indiana.

The Technical Project Manager will transfer to the new facility site upon commencement of construction.

In addition to managing the facility build, this role will have a significant focus on overseeing the integration and commissioning of advanced manufacturing technologies and systems critical to radiopharmaceutical production.

The candidate will work closely with the Head of Program Management, the Head of Capital Project Engineering, and the Bristol Myers Squibb team to ensure alignment across all technical, engineering, and operational aspects of the project.

The ideal candidate will possess in-depth knowledge of clean room design, operation, and regulatory requirements, as well as hands-on experience with the installation and commissioning of hot cells for radiopharmaceutical manufacturing.

The Technical Project Manager will ensure all phases of facility construction and transition to production are delivered on schedule, within scope, and in compliance with regulatory and quality standards.

This position reports directly to the Head of Program Management.

Job Responsibilities

• Lead end-to-end project management for the construction and commissioning of a new radiopharmaceutical manufacturing site and process technologies, from design through validation and production launch.

• Track facility construction activities, coordinating with contractors, architects, engineers, and internal stakeholders.

• Serve as the primary liaison between construction teams, manufacturing operations, engineering, and regulatory affairs to ensure alignment and timely decision-making.

• Develop and manage detailed project timelines, budgets, and resource allocations; proactively identify and mitigate risks.

• Ensure all facility design and construction activities adhere to Good Manufacturing Practices (GMP) and regulatory requirements for radiopharmaceutical production.

• Manage internal and external project teams, providing clear direction, accountability, and communication.

• Prepare and deliver regular updates and presentations to the Head of Program Management, executive leadership, and external partners.

• Plan and facilitate the transition from construction to operational readiness, including facility qualification, equipment validation, and staff training.

• Implement project management tools and best practices for tracking progress, reporting, and documentation.

• Foster a culture of safety and compliance, ensuring all personnel follow environmental, health, and safety (EHS) protocols, including the use of PPE in radioactive material environments.

Education and Experience

• Bachelor’s degree in engineering (civil, mechanical, chemical, or related field) required.

• Minimum of 5 years of project management experience in pharmaceutical or radiopharmaceutical manufacturing, with direct responsibility for facility construction or major capital projects ranging from $10 million to $150 million.

• In-depth knowledge of GMP, FDA requirements, and regulatory considerations for radiopharmaceuticals.

• Prior experience managing large-scale construction projects in a regulated manufacturing environment.

Skills and Qualifications

• Proficient with project management tools and software (e.g., MS Office – Microsoft Project, ERP systems such as SAP).

• Strong knowledge of radiopharmaceutical production processes and facility operational requirements.

• Excellent organizational, multitasking, and analytical skills.

• Ability to lead cross-functional teams and effectively communicate at all organizational levels.

• Demonstrated ability to handle confidential information and manage complex stakeholder relationships.

• Strong long-term planning, resource management, and risk mitigation abilities.

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear.

The employee must occasionally lift and/or move up to 50 pounds.

Specific vision abilities required by this job include close vision and distance vision.

Must be willing to wear personal protective equipment (PPE) for long periods.

This is a position that may require working in a laboratory environment, protective clothing, gloves, and safety glasses are required while working in a laboratory environment with radioactive materials.

Work Environment

The noise level in the work environment is usually moderate.

96,148 - $116,500

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Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary.

Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work.

This structure includes site-essential, site-by-design, field-based and remote-by-design jobs.

The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility.

Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility.

For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.

For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles.

Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to .

Visit to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities.

As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Required Skill Profession

Operations Specialties Managers