HMS Postdoctoral Fellow in Genetics

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Title HMS - Postdoctoral Fellow in Genetics

School Harvard Medical School

Department/Area ***

Position Description
We invite applicants for a postdoctoral fellow position in the Sinclair Lab at Harvard Medical School in Boston Massachusetts.


The Sinclair lab is known for their work on genes and small molecules that delay or reverse aging.

They have identified a new approach to safely reverse the age of tissues and used it to restore the vision of old mice, a study that was recently on the cover of Nature.

The lab has a wide range of expertise and interests, including cancer, neurodegeneration, blindness, diabetes, and muscle degeneration.

We welcome applications from recent PhD graduates who are interested in these or related fields, particularly those who may bring a new technology or perspective to bear on the work in the lab.

The successful candidate will work with Dr. David Sinclair to develop an independent research project within the scope of the lab’s focus on aging, genetics, and epigenetic reprogramming.

In addition to carrying out bench research involving genetics and genomics, molecular and cellular biology techniques, epigenetics, and small animal husbandry, the successful candidate will be expected to apply for fellowship funding, contribute to the writing of grants and manuscripts, and participate in the mentoring and training of lab members as needed.

The candidate will also contribute to the development and application of new approaches to safely reverse aging and treat both rare and common diseases, while actively supporting the collaborative and innovative environment of the lab.

Salary and Benefits

This position is salaried and benefits eligible.

Information regarding postdoctoral fellow salary, which is determined by the number of years post PhD, and benefits can be found at https://postdoc.hms.harvard.edu/guidelines.


With this appointment, you are represented by the Harvard Academic Workers ( HAW ) – UAW for purposes of collective bargaining and matters affecting your compensation and working conditions.


Basic Qualifications

+ Required Skills/Abilities/Competencies:

+ A Ph.D. in genetics, molecular biology, biochemistry, genomics, neuroscience, systems biology, or related.

+ Strong scientific knowledge of molecular and cellular biology, genetics and epigenetics or neuroscience.

+ Experience with small animal husbandry.

+ Outstanding personal initiative and creativity.

+ Ability to interpret complex data sets and design subsequent experiments.

• Excellent teamwork, time management and organizational skills.

+ Ability to work independently in a multidisciplinary, fast- paced, results-oriented environment.

+ Talent in presenting data to a multidisciplinary audience in a clear and cohesive manner.

+ Ability to meet deadlines and multitask efficiently is a must



Additional Qualifications

Special Instructions
Required documents:


+ Curriculum Vitae

+ Statement of Research for PhD work

+ Cover Letter describing your interest in the lab and initial ideas for new research directions or projects you could undertake in the lab.

+ Note with names and contact information for three people who have agreed to serve as your reference


Please submit application documents through the ARIeS portal.

Applications will be considered 10/29/2025.

Selected candidates will be invited for in-person interviews involving a research presentation on past work.

Expected Dates


+ Application deadline: 10/31/2025– at least 15 business days after posting

+ Start date: The position is expected to start on or about 2/2/2026 with some flexibility.

+ Duration: This is a one-year term position from the date of hire, with the possibility of extension, contingent upon work performance, business need, and continued funding to support the position.



Contact Information
Genetics Hire Team; Luis Rajman; NRB -931C NRB building, 77 Ave Louis Pasteur, Boston, MA 02115


Contact Email luis_rajman@hms.harvard.edu

Salary Range
Information regarding postdoctoral fellow salary, which is determined by the number of years post PhD, can be found at https://postdoc.hms.harvard.edu/guidelines.


Minimum Number of References Required 3

Maximum Number of References Allowed 6

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